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Heartgard Plus Chewables

4.8 / 5
Reviews: 139
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HeartGard Plus Chewables for Dogs - Heartworm Chew

Heartgard Plus Chewable for Dogs - Heartworm Prevention Chew

HeartGard Plus for dogs is a vet-recommended heartworm preventive treatment that also controls and treats various other worm infections. It is effective against immature stages of heartworm that is transmitted through a mosquito. It also treats and controls three species of hookworms and two species of roundworms. This monthly treatment has antiparasitic and anthelmintic properties that work against mixed parasitic infections. It comes in a real beef flavor which makes it highly palatable in taste for the dogs. This monthly treatment is one of the most recommended heartworm preventative treatments and it is safe and suitable for dogs 6 weeks of age and older as well as breeding and pregnant dogs.

How does it work?

Heartgard Plus contains two active ingredients Ivermectin and Pyrantel. It is an effective heartworm treatment for dogs that prevents heartworm disease by eliminating heartworm larvae and kills parasites by causing spastic muscle paralysis. These active chemicals control the way nerve impulses flow through the neurological system of the worm. This causes the parasite to become paralyzed and eventually die.

It should be noted that Heartgard Plus is only effective as a preventative for heartworm infection. You must first diagnose your dog for heartworm infection before administering any heartworm prevention product. If your dog has already been infected with heartworm, you should consult your veterinarian.

  • Heartworm testing is recommended prior to beginning treatment.
  • Weigh your pet and choose the appropriate pack based on your dog’s weight. (Refer the below given dosage table for details)
  • Only remove a single chewable from the foil blister at a time.
  • Place the rest of the chewables back in the box to store out of light.
  • Give Heartgard Plus Chewable once a month on the same day of each month year round.
  • Heartgard Plus Chewable should not be swallowed whole.
  • Chewables may be broken and fed to dogs as pieces, or crumbled and mixed with food.
  • Administer in the way that encourages your dog to chew instead of swallow.
  • Ensure that your dog consumes the full dose, and then observe afterward to be sure none is rejected or lost. If any portion of the dose is lost, re-dose.
  • To switch from another heartworm preventative to HEARTGARD Plus, administer this treatment within 30 days of the final dose of your dog's old preventative.
  • If your dog goes more than 30 days without heartworm prevention, the efficacy of the ingredient Ivermectin may be lower. For this reason, the treatment should be administered monthly on the same day each month.
  • If your dog's treatment is delayed by a few or several days, treat immediately and resume the recommended schedule to mitigate potential adult heartworm development.

Dosage Table:

Pack Color Dog Weight Dog Size Strength
Blue Up to 11kg Small Dogs 68 mcg of Ivermectin and 57 mg of Pyrantel
Green 12 to 22kg Medium Dogs 136 mcg of Ivermectin and 114 mg of Pyrantel
Brown 23 to 45kg Large Dogs 272 mcg of Ivermectin and 227 mg of Pyrantel

HEARTGARD Plus is recommended for dogs 6 weeks of age and older. For dogs over 45kg use the appropriate combination of tablets based on weight.

  • Single chewable works for a full month
  • #1 Vet-recommended heartworm disease preventative
  • Protects dogs and puppies from potentially dangerous heartworm disease
  • Protects against intestinal worms such as roundworms and hookworms
  • Formulated in chewable form for easy administration
  • Pairs perfectly with any proven flea and tick treatment
  • Highly palatable in taste due to its real beef flavor
  • Suitable to be given to pregnant or breeding female dogs
  • Heartgard Plus Chewables are for dogs only. Do not give to cats.
  • Dog should be tested by veterinarian before heartworm prevention is initiated.
  • Read the enclosed leaflet before using the product.
  • Although side effects are rare but may show up in hypersensitive canines. Overdosing may result in tremors, dilated pupil, and weight loss.
  • Avoid contact with eyes.
  • Wash hands after use.
  • Do not freeze. Protect from direct sunlight.
  • Human ingestion may prove poisonous. If such cases arise then consult a physician immediately.
  • In case the dosage is missed for more than two months, you need to consult a veterinarian and take his advice for further treatment.

Caution: Collies including Border Collies and other breeds have genetic intolerance to Ivermectin. Those pet parents with Collies and other susceptible breeds should consult a veterinarian before administering any treatment containing Ivermectin.

Target Species 6 weeks and older puppies and dogs
Mode of administration Oral
Active Ingredients Ivermectin and Pyrantel
Manufacturer Boehringer Ingelheim
Brand Name Heartgard Plus

APVMA Approval Number

Heartgard Plus Chewables For Small Dogs Up To 11Kg (Blue) 39541/100433
Heartgard Plus Chewables For Medium Dogs 12 To 22 Kg (Green) 39540/100436
Heartgard Plus Chewables For Large Dog 23 To 45 Kg (Brown) 39539/100435
Product Reviews
Reviews: 139
5 Star 4 Star 3 Star 2 Star 1 Star

Heartgard Plus Chewables

Heartgard Plus Chewables

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Tasty chewable treatment

This treatment is a tasty treat for my canine. He eagerly takes this chewable. It not only protects him from heartworm, but also round worm and hook worm. I love the fact that my dog is protected from all these nasty worms with one simple chew that he finds delicious.


Best deworming brand

This is the best preventive treatment for heartworm infection. It is very effective product, it also helps to eliminate the internal parasites. I am very content with this product as there are no side effects and completely working well on my pooch. I like to purchase the products from VetSupply as I appreciate the price discount and the easiness of ordering online. Thank you very much!!


Awesome Product

My vet had suggested me to use this product to protect my pooch from heartworms as well as to control gastrointestinal worms. It is easy to give him as a monthly treatment. This comes with little heart stickers to put on your calendar for reminders on when the next doses are due. Nothing is as good as this preventive for my furry buddy!!!


Reliable heartworm prevention

I have two dogs, so I was looking for 100% reliable heartworm prevention. As there is heartworm infestation in my area, and my doggies have never caught this disease. I can say that this product is working very well on my furry pals. I am content with the results


Excellent and very effective product

Advantage is very effective in breaking the life cycle of fleas that I have not had to use any other flea protection on my dog. Previously, I was facing many problems with the other flea treatments and which was incurring more expense as the fleas cycle was never broken. I purchased Advantage from VetSupply because I get this effective product on lowest price and free shipping too.

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